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Phenotypes Associated with This Genotype
Genotype
MGI:6382792
cn1
Allelic
Composition		 Sod2tm1Kskk/Sod2tm1Kskk
Tg(BEST1-rtTA,tetO-cre)1Yzl/0
Genetic
Background		 B6.Cg-Sod2tm1Kskk Tg(BEST1-rtTA,tetO-cre)1Yzl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sod2tm1Kskk mutation (0 available); any Sod2 mutation (26 available)
Tg(BEST1-rtTA,tetO-cre)1Yzl mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
retina pigment epithelium atrophy ( J:282248 )
• at age 6 and 9 months after doxycycline administration
thin retina outer nuclear layer ( J:282248 )
• at age 6 and 9 months after doxycycline administration
retina degeneration ( J:282248 )
• at age 6 and 9 months after doxycycline administration
decreased a-wave amplitude ( J:282248 )
• at age 6 and 9 months after doxycycline administration
decreased b-wave amplitude ( J:282248 )
• at age 6 and 9 months after doxycycline administration

pigmentation
retina pigment epithelium atrophy ( J:282248 )
• at age 6 and 9 months after doxycycline administration

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory