Phenotypes Associated with This Genotype

Genotype
MGI:6384940

tg2

• Allelic Composition: Tg(CAG-COX7A2L)#Sinos/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased carbon dioxide production ( J:215964 )

• mice show an increase in CO2 production (VCO2) in the steady state

increased oxygen consumption ( J:215964 )

• mice show an increase in oxygen consumption (VO2) in the steady state

increased aerobic running capacity ( J:215964 )

• mice show 130% of the running capacity in the forced treadmill test

abnormal enzyme/coenzyme activity ( J:215964 )

• cytochrome c oxidase (COX) activity is enhanced in MEFs

cellular

increased fibroblast proliferation ( J:215964 )

• cell proliferation is enhanced in MEFs

adipose tissue

adipose tissue phenotype ( J:215964 )

N • brown adipose tissue weights are similar to wild-type mice