Phenotypes Associated with This Genotype

Genotype
MGI:6423511

• Allelic Composition: Mir140^em1Tkob/Mir140⁺
• Genetic Background: C57BL/6-Mir140^em1Tkob

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

platyspondylia ( J:286036 )

• mice show mildly flat vertebral bodies

abnormal cartilage development ( J:286036 )

• mice show delayed cartilage maturation of the larynx, trachea, and anterior ribs

abnormal epiphyseal plate morphology ( J:286036 )

• basal skull growth plate is wider due to increased length of all layers of chondrocytes

abnormal long bone epiphyseal plate morphology ( J:286036 )

• proximal tibial growth plates show an expansion of the resting zone

delayed bone ossification ( J:286036 )

• mice show delayed secondary ossification of tubular and carpal bones

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
osteochondrodysplasia		DOID:2256		J:286036