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Phenotypes Associated with This Genotype
Genotype
MGI:6433773
Allelic
Composition		 Ppp1r14ctm1Uhl/Ppp1r14ctm1Uhl
Genetic
Background		 B6;129S6-Ppp1r14ctm1Uhl/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppp1r14ctm1Uhl mutation (1 available); any Ppp1r14c mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to Coronaviridae infection ( J:288523 )
• mice infected with the mouse-adapted SARS-CoV MA15 exhibit more weight loss than wild-type mice and a moderate, but insignificant, increase in viral titers

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
Coronavirus infectious disease DOID:0080599 J:288523

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory