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Phenotypes Associated with This Genotype
Genotype
MGI:6456933
cn3
Allelic
Composition		 Chd3tm1.1Cya/Chd3tm1.1Cya
Chd4tm1.1Kge/Chd4tm1.1Kge
Tg(Tek-cre)1Ywa/0
Genetic
Background		 involves: C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chd3tm1.1Cya mutation (0 available); any Chd3 mutation (103 available)
Chd4tm1.1Kge mutation (0 available); any Chd4 mutation (58 available)
Tg(Tek-cre)1Ywa mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal blood vessel morphology ( J:294633 )
• vascular rupture in E11.5 embryos
• normal vasculature in E10.5 embryos
hemorrhage ( J:294633 )
• in E11.5 embryos

mortality/aging
embryonic lethality, complete penetrance ( J:294633 )
• most embryos die between age E10.5-11.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory