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Phenotypes Associated with This Genotype
Genotype
MGI:6472964
Allelic
Composition
Agxttm1Ull/Agxttm1Ull
Genetic
Background
involves: 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agxttm1Ull mutation (0 available); any Agxt mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• both males and females exhibit an increase in urinary oxalate excretion, with males excreting 2-fold more urinary oxalate than females

renal/urinary system
• both males and females exhibit an increase in urinary oxalate excretion, with males excreting 2-fold more urinary oxalate than females

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
primary hyperoxaluria type 1 DOID:0111670 OMIM:259900
J:283585


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory