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Phenotypes Associated with This Genotype
Genotype
MGI:6507171
ht2
Allelic
Composition
Phf6tm1.2Avo/Phf6+
Genetic
Background
involves: BALB/cJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Phf6tm1.2Avo mutation (0 available); any Phf6 mutation (12 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• mice show an earlier onset of hematopoietic neoplasms that spontaneously occur in wild-type mice
• tumors are localized to the liver, spleen, and/or lymph nodes
• tumors express T-cell, B-cell, or myeloid/erythroid cell surface makers or show aberrant expression of markers from multiple hematopoietic lineages

growth/size/body
• females show reduced body weight by 3 weeks of age


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory