Phenotypes for Ppil1 MGI:6509640 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ppil1^em4Jgg/Ppil1^em4Jgg
Genetic Background	C57BL/6-Ppil1^em4Jgg

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppil1^em4Jgg mutation (0 available); any Ppil1 mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

increased neuron apoptosis ( J:300487 )

• in embryonic brain

loss of cortex neurons ( J:300487 )

thin cerebral cortex ( J:300487 )

mortality/aging

growth/size/body

microcephaly ( J:300487 )

cellular

increased neuron apoptosis ( J:300487 )

• in embryonic brain

Mouse Models of Human Disease	DO ID	OMIM ID(s)	Ref(s)
microcephaly	DOID:10907		J:300487
pontocerebellar hypoplasia type 14	DOID:0112325	OMIM:619301	J:300487

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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