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Phenotypes Associated with This Genotype
Genotype
MGI:6693346
hm1
Allelic
Composition		 Nemp1em1Hmc/Nemp1em1Hmc
Genetic
Background		 C57BL/6N-Nemp1em1Hmc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nemp1em1Hmc mutation (0 available); any Nemp1 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:303621 )
N
• male mice are fertile
abnormal oocyte morphology ( J:303621 )
• reduced nuclear envelop stiffness
abnormal female meiosis ( J:303621 )
• increasing with maternal age
female infertility ( J:303621 )
• female mice are infertile or subfertile
reduced female fertility ( J:303621 )
• female mice are infertile or subfertile

hematopoietic system

endocrine/exocrine glands

cellular
abnormal oocyte morphology ( J:303621 )
• reduced nuclear envelop stiffness
abnormal female meiosis ( J:303621 )
• increasing with maternal age
maternal effect ( J:303621 )
• zygotes from null oocytes fertilized with wild-type sperm fail to develop beyond the 8 cell stage

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory