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Phenotypes Associated with This Genotype
Genotype
MGI:6693728
hm1
Allelic
Composition
Dnpepem1Dlp/Dnpepem1Dlp
Genetic
Background
involves: C57BL/6 * C57BL/6J * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnpepem1Dlp mutation (1 available); any Dnpep mutation (35 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• homozygous mutant mice are viable and overtly normal; isolated kidney lysates retain cleavage activity of a recombinant GST-STK39 fusion protein, indicating that a protease other than DNPEP also mediates proteolytic cleavage of STK39 (also known as SPAK, STE20/SPS1-related proline/alanine-rich kinase)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory