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Phenotypes Associated with This Genotype
Genotype
MGI:6712737
cn2
Allelic
Composition		 Il22ra1tm1.1Koll/Il22ra1tm1.1Koll
Riok2tm1c(KOMP)Wtsi/Riok2+
Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic
Background		 involves: C57BL/6N * C57BL/10 * CBA/Ca
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Commd10Tg(Vav1-icre)A2Kio mutation (4 available); any Commd10 mutation (25 available)
Il22ra1tm1.1Koll mutation (1 available); any Il22ra1 mutation (32 available)
Riok2tm1c(KOMP)Wtsi mutation (0 available); any Riok2 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:305794 )
N
• mice show an improvement in peripheral blood red blood cell numbers and hematocrit levels, and an increase in RIII and RIV erythroid precursors in the bone marrow compared to Il22ra1-sufficient Riok2-haploinsufficent mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory