About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:6727110
Allelic
Composition
Cfap47em1Fzh/Y
Genetic
Background
C57BL/6-Cfap47em1Fzh
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cfap47em1Fzh mutation (0 available); any Cfap47 mutation (6 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• frequent occurrence of bent flagella
• higher rate of unevenly distributed fibrous sheath
• frequent occurrence of bent flagella
• diminished and abnormal sperm motility and progressive motility with high rate of immotile and non-progressive spermatozoa
• significantly reduced curvilinear velocity (VCL), straight-line velocity (VSL), and average-path velocity (VAP)
• sperm can fertilize eggs through intra-cytoplasmic sperm injection (ICSI) or, at a lower rate, in vitro fertilization (IVF)
• no offspring when mated to WT females

cellular
• frequent occurrence of bent flagella
• higher rate of unevenly distributed fibrous sheath
• frequent occurrence of bent flagella
• diminished and abnormal sperm motility and progressive motility with high rate of immotile and non-progressive spermatozoa
• significantly reduced curvilinear velocity (VCL), straight-line velocity (VSL), and average-path velocity (VAP)

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
male infertility DOID:12336 J:307391


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory