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Phenotypes Associated with This Genotype
Genotype
MGI:6766589
Allelic
Composition		 Hand1tm5Abfi/Hand1+
Tg(Mef2c-cre)2Blk/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hand1tm5Abfi mutation (0 available); any Hand1 mutation (15 available)
Tg(Mef2c-cre)2Blk mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal cardiac outflow tract development ( J:311466 )
• elongated outflow tract
decreased heart right ventricle size ( J:311466 )
• right ventricle size appears reduced at E14.5 and at P60
• however, mice exhibit a normal left ventricle chamber

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
NOT hypoplastic left heart syndrome DOID:9955 OMIM:241550
OMIM:614435
 J:311466

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory