Phenotypes for Cdkn2a Fbxw11 MGI:6781883 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp Fbxw11^tm1Nakay/Fbxw11^tm1Nakay
Genetic Background	B6.Cg-Cdkn2a^tm1Rdp Fbxw11^tm1Nakay

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn2a^tm1Rdp mutation (6 available); any Cdkn2a mutation (66 available)
Fbxw11^tm1Nakay mutation (0 available); any Fbxw11 mutation (72 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:228222 )

• phenotype is stated to be identical to that of Fbxw11^tm1Nakay homozygotes, indicating that concomitant inactivation of Cdkn2a does not rescue the lethal phenotype

embryo

embryonic growth arrest ( J:228222 )

embryonic growth retardation ( J:228222 )

growth/size/body

embryonic growth retardation ( J:228222 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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