Analysis Tools
cellular
|
• when cultured on fibronectin-coated plates, inter-follicular epidermis melanocytes exhibit reversable increased survival compared with wild-type mice
• impaired melanocyte survival and production of long, breakable and fragmentable dendrites when co-cultured with inter-follicular epidermis
• however, melanocytes exhibit normal migration and extension/retraction of protrusions when co-cultured with inter-follicular epidermis
|
|
• impaired proliferation when melanocytes are co-cultured with inter-follicular epidermis
|
integument
pigmentation
|
• impaired proliferation when melanocytes are co-cultured with inter-follicular epidermis
|
|
• more dendritic morphology with increased protrusions per cell
• some cells in culture adopt a round shape unlike wild-type cells
• melanocytes grown with mouse embryonic fibroblasts exhibit larger and irregular shapes compared with wild-type cells
|
limbs/digits/tail
