Phenotypes Associated with This Genotype

Genotype
MGI:6865691

• Allelic Composition: Prkcg^em1Jpka/Prkcg⁺
• Genetic Background: FVB/N-Prkcg^em1Jpka

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

ataxia ( J:305637 )

• mice show marked ataxia at 3 and 6 months of age on the balance beam test

abnormal gait ( J:305637 )

• footprint gait analysis of 9-month-old mice shows an ataxic gait with increased step width

nervous system

abnormal Purkinje cell dendrite morphology ( J:305637 )

• dendritic expansion of Purkinje cells in organotypic slice culture is severely impaired and cells develop only short thickened dendrites

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
spinocerebellar ataxia type 14		DOID:0050964	OMIM:605361	J:305637