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Phenotypes Associated with This Genotype
Genotype
MGI:6887369
cx2
Allelic
Composition
Slc9a8tm1d(KOMP)Wtsi/Slc9a8tm1d(KOMP)Wtsi
Tg(CAG-RFP,Acr-EGFP)RBGS002Osb/0
Genetic
Background
involves: C57BL/6 * C57BL/6N * DBA/2
Cell Lines EPD0033_5_A07
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc9a8tm1d(KOMP)Wtsi mutation (0 available); any Slc9a8 mutation (108 available)
Tg(CAG-RFP,Acr-EGFP)RBGS002Osb mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• mature spermatozoa show abnormal mitochondrial distribution: mitochondria are found in sperm heads instead of forming a sheath around the initial part of the sperm tail
• mature spermatozoa isolated from the caudae epididymides lack acrosomes

cellular
• mature spermatozoa show abnormal mitochondrial distribution: mitochondria are found in sperm heads instead of forming a sheath around the initial part of the sperm tail
• mature spermatozoa isolated from the caudae epididymides lack acrosomes


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory