Phenotypes for Tg(Atoh1-cre)1Bfri Tubb4a MGI:6888390 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Tubb4a^Jit/Tubb4a^{tm1c(EUCOMM)Hmgu} Tg(Atoh1-cre)1Bfri/0
Genetic Background	involves: C57BL/6 * C57BL/6N * CBA * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Atoh1-cre)1Bfri mutation (1 available)
Tubb4a^Jit mutation (0 available); any Tubb4a mutation (30 available)
Tubb4a^{tm1c(EUCOMM)Hmgu} mutation (0 available); any Tubb4a mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal cerebellar granule cell morphology ( J:321692 )

• loss of granule cell neurons

• however, no reduction of myelination levels is seen

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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