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Phenotypes Associated with This Genotype
Genotype
MGI:7281516
cn1
Allelic
Composition		 Ptpn11tm1Gsf/Ptpn11tm1Gsf
Tg(Inha-cre)3Zuk/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptpn11tm1Gsf mutation (0 available); any Ptpn11 mutation (46 available)
Tg(Inha-cre)3Zuk mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
seminiferous tubule degeneration ( J:250152 )
• tubules exhibit a damaged structure by 8 weeks of age
small testis ( J:250152 )
• at 3 weeks of age, testes are significantly smaller than those in control males

endocrine/exocrine glands
seminiferous tubule degeneration ( J:250152 )
• tubules exhibit a damaged structure by 8 weeks of age
small testis ( J:250152 )
• at 3 weeks of age, testes are significantly smaller than those in control males

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory