Phenotypes for Adar Meox2 MGI:7281842 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Adar^em1Stsn/Adar^tm1.1Phs Meox2^tm1(cre)Sor/Meox2⁺
Genetic Background	involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adar^em1Stsn mutation (0 available); any Adar mutation (72 available)
Adar^tm1.1Phs mutation (2 available); any Adar mutation (72 available)
Meox2^tm1(cre)Sor mutation (3 available); any Meox2 mutation (18 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body size ( J:308678 )

• at weaning

mortality/aging

lethality, complete penetrance ( J:308678 )

• no survival beyond ~84 days

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Aicardi-Goutieres syndrome		DOID:0050629	OMIM:225750 OMIM:610181 OMIM:610329 OMIM:610333 OMIM:612952 OMIM:615010 OMIM:615846 OMIM:PS225750	J:308678

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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