About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:7286375
Allelic
Composition		 Specc1lem3Kumc/Specc1l+
Genetic
Background		 involves: C57BL/6J * FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Specc1lem3Kumc mutation (0 available); any Specc1l mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, incomplete penetrance ( J:324294 )
• Background Sensitivity: rarely see females at weaning when backcrossed to C57BL/6 for approximately 6 generations

craniofacial
cleft palate ( J:324294 )
• low level of penetrance

digestive/alimentary system
cleft palate ( J:324294 )
• low level of penetrance

growth/size/body
cleft palate ( J:324294 )
• low level of penetrance
omphalocele ( J:324294 )
• low level of penetrance

vision/eye
coloboma ( J:324294 )
• low level of penetrance

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
cleft palate DOID:674 J:324294

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory