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Phenotypes Associated with This Genotype
Genotype
MGI:7309156
Allelic
Composition
Zng1em2Skan/Zng1em2Skan
Genetic
Background
C57BL/6N-Zng1em2Skan
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zng1em2Skan mutation (0 available); any Zng1 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
renal/urinary system
• 60% of mice exhibit identifiable congenital anomalies of the kidney and urinary tract (CAKUT) phenotypes
• hyperplasia of the renal interstitium is seen in the kidney
• pups show hydronephrosis
• construction of rental tubules is disrupted
• duplicated ureters in 4-week-old mice
• pups show hydroureter

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
CAKUT DOID:0080205 OMIM:PS610805
J:326010


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory