Phenotypes Associated with This Genotype

Genotype
MGI:7310219

hm1

• Allelic Composition: Drc1^em2Mngx/Drc1^em2Mngx
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:322334 )

• all mice exhibit prepuberal death, usually before P12

• Background Sensitivity: postnatal survival is significantly extended on a C57BL/6 x ICR genetic background

growth/size/body

decreased body size ( J:322334 )

• at P14, mice are significantly smaller than wild-type controls

postnatal growth retardation ( J:322334 )

• mice show obvious signs of growth retardation

nervous system

hydrocephaly ( J:322334 )

• all mice show obvious signs of hydrocephalus