Phenotypes Associated with This Genotype

Genotype
MGI:7329919

• Allelic Composition: Usp45^em1Qzha/Usp45^em1Qzha
• Genetic Background: C57BL/6J-Usp45^em1Qzha

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

decreased retina cone cell number ( J:282594 )

• mice exhibit fewer cones by 20 weeks of age

abnormal cone electrophysiology ( J:282594 )

• mice show severely reduced photopic response

abnormal rod electrophysiology ( J:282594 )

• mice show severely reduced scotopic response

nervous system

decreased retina cone cell number ( J:282594 )

• mice exhibit fewer cones by 20 weeks of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Leber congenital amaurosis 19		DOID:0081169	OMIM:618513	J:282594