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Phenotypes Associated with This Genotype
Genotype
MGI:7331485
hm1
Allelic
Composition		 Sar1bem1Emle/Sar1bem1Emle
Genetic
Background		 C57BL/6N-Sar1bem1Emle
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sar1bem1Emle mutation (0 available); any Sar1b mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality throughout fetal growth and development, incomplete penetrance ( J:319817 )
• only 12% versus the expected 25% of homozygotes are obtained, with pups dead at birth indicating late-gestation lethality

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory