homeostasis/metabolism
• mice exhibit reduced triglyceride concentration after olive oil intragastric administration indicating intestinal fat malabsorption
• an increase in triglyceride and total cholesterol is seen in the gut following fat load
|
• mice show an increase in non-HDL cholesterol
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• protein and gene expression analysis shows altered intestinal, but not liver, lipid metabolism, with a plausible enhancement of fatty acid beta-oxidation in the intestine and decline in lipogenesis process
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• chylomicron lipid content shows lower triglyceride and total cholesterol content, indicating depressed chylomicron output
|
digestive/alimentary system
• mice exhibit reduced triglyceride concentration after olive oil intragastric administration indicating intestinal fat malabsorption
• an increase in triglyceride and total cholesterol is seen in the gut following fat load
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
chylomicron retention disease | DOID:0060357 |
OMIM:246700 |
J:319817 |