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Phenotypes Associated with This Genotype
Genotype
MGI:7388555
Allelic
Composition
Mettl23em1Itwa/Mettl23em1Itwa
Genetic
Background
C57BL/6J-Mettl23em1Itwa
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mettl23em1Itwa mutation (0 available); any Mettl23 mutation (21 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• mice exhibit normal intraocular pressure
• significant at 6 months of age
• severe at 2 months of age
• reduced ganglion cell complexes at 2 and 6 months of age with progressive axonal loss
• reduced pSTR amplitudes of scotopic ERG at 6 months of age

nervous system
• significant at 6 months of age
• severe at 2 months of age

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
glaucoma DOID:1686 J:330971


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory