Phenotypes for Rr124128 Tg(Pdx1-cre)6Tuv MGI:7431290 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Rr124128^tm1.1Jfer/Rr124128^tm1.1Jfer Tg(Pdx1-cre)6Tuv/0
Genetic Background	involves: C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr124128^tm1.1Jfer mutation (0 available); any Rr124128 mutation (0 available)
Tg(Pdx1-cre)6Tuv mutation (3 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

growth/size/body region phenotype ( J:332319 )

N	• normal growth and morphology

homeostasis/metabolism

hyperglycemia ( J:332319 )

• fasting hyperglycaemia by age 8 weeks

decreased circulating insulin level ( J:332319 )

• insulin deficiency by age 8 weeks

impaired glucose tolerance ( J:332319 )

• glucose intolerance by age 8 weeks

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
diabetes mellitus		DOID:9351		J:332319

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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