Analysis Tools
reproductive system
 N |
• normal testis size and descendance and vas deferens development in E18.5 embryos
|
|
|
• few mature spermatozoa in seminiferous tubules in adult mice
|
|
|
• mostly replaced with adipose tissue in adult mice
|
 |
• in adult mice
|
|
|
• many traces of closed follicles in adult mice
|
small ovary
(
J:334319
)
|
|
• in adult mice
|
|
|
• reduced diameter in adult mice
|
|
|
• fewer lipid droplets in interstitial Leydig cells in adult mice
|
small testis
(
J:334319
)
|
|
• in adult mice
|
|
|
• narrower testicular interstitium area in adult mice
|
small penis
(
J:334319
)
|
|
• in adult mice
|
infertility
(
J:334319
)
endocrine/exocrine glands
|
N |
• normal adrenal gland size in E18.5 embryos
|
|
|
• mostly replaced with adipose tissue in adult mice
|
|
|
• in adult mice
|
|
|
• many traces of closed follicles in adult mice
|
small ovary
(
J:334319
)
|
|
• in adult mice
|
|
|
• reduced diameter in adult mice
|
|
|
• fewer lipid droplets in interstitial Leydig cells in adult mice
|
small testis
(
J:334319
)
|
|
• in adult mice
|
|
|
• narrower testicular interstitium area in adult mice
|
homeostasis/metabolism
|
N |
• normal intratesticular testosterone, androstenedione and other steroid concentrations in E18.5 embryos
|
|
|
• in adult mice
|
|
|
• reduced intratesticular dehydroepiandrosterone, androstenediol, 7alpha-hydroxyandrostenedione, androstenedione and testosterone levels in adult mice
• normal intratesticular testosterone, androstenedione and other steroid concentrations in E18.5 embryos
|
cellular
|
|
• few mature spermatozoa in seminiferous tubules in adult mice
|
renal/urinary system
small penis
(
J:334319
)
|
|
• in adult mice
|
nervous system
| N |
• normal pituitary gland size in adult mice
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| infertility | DOID:5223 | J:334319 | ||
| male infertility | DOID:12336 | J:334319 | ||
