Phenotypes Associated with This Genotype

Genotype
MGI:7451325

• Allelic Composition: Sox9^tm1.2Ksec/Sox9⁺
• Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired swimming ( J:332093 )

circling ( J:332093 )

hearing/vestibular/ear

abnormal endolymphatic duct morphology ( J:332093 )

• reduced proportions of mitochondrial-rich and ribosomal-rich mature cells and concomitant increase immature cells in endolymphatic sac in E14.5 embryos

limbs/digits/tail

kinked tail ( J:332093 )

mortality/aging

perinatal lethality ( J:332093 )

• only ~10% of mice survive

skeleton

chondrodystrophy ( J:332093 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
campomelic dysplasia		DOID:0050463	OMIM:114290	J:332093