Phenotypes Associated with This Genotype

Genotype
MGI:7467143

• Allelic Composition: Cdh5^tm1Dvst/Cdh5^tm1Dvst; Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

decreased angiogenesis ( J:328283 )

• delayed superficial blood vessel growth in retina at age P7 after tamoxifen administration from age P1-P4

increased angiogenesis ( J:328283 )

• local blood vessel hyperdensity in retina at age P7 after tamoxifen administration from age P1-P4

hemorrhage ( J:328283 )

• extensive blood leakage in retina at age P7 after tamoxifen administration from age P1-P4

vision/eye

abnormal retina development ( J:328283 )

• delayed superficial blood vessel growth at age P7 after tamoxifen administration from age P1-P4

• local blood vessel hyperdensity at age P7 after tamoxifen administration from age P1-P4

• extensive blood leakage at age P7 after tamoxifen administration from age P1-P4

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
exudative vitreoretinopathy		DOID:0050535	OMIM:PS133780	J:328283