Phenotypes Associated with This Genotype

Genotype
MGI:7551075

hm1

• Allelic Composition: Clcn1^em1(IMPC)Mbp/Clcn1^em1(IMPC)Mbp
• Genetic Background: C57BL/6NCrl-Clcn1^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Clcn1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal behavior ( J:211773 )

♂

IMPC - UCD

decreased exploration in new environment ( J:211773 )

♀

IMPC - UCD

decreased thigmotaxis ( J:211773 )

♂

IMPC - UCD

decreased startle reflex ( J:211773 )

IMPC - UCD

tremors ( J:211773 )

IMPC - UCD

decreased grip strength ( J:211773 )

IMPC - UCD

abnormal gait ( J:211773 )

IMPC - UCD

decreased vertical activity ( J:211773 )

IMPC - UCD

decreased locomotor activity ( J:211773 )

IMPC - UCD

cardiovascular system

decreased heart weight ( J:211773 )

♂

IMPC - UCD

growth/size/body

decreased body length ( J:211773 )

IMPC - UCD

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - UCD

hematopoietic system

increased eosinophil cell number ( J:211773 )

IMPC - UCD

decreased mean platelet volume ( J:211773 )

IMPC - UCD

decreased lymphocyte cell number ( J:211773 )

IMPC - UCD

decreased monocyte cell number ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

IMPC - UCD

decreased circulating glucose level ( J:211773 )

♂

IMPC - UCD

increased circulating aspartate transaminase level ( J:211773 )

IMPC - UCD

increased circulating serum albumin level ( J:211773 )

♂

IMPC - UCD

abnormal cholesterol homeostasis ( J:211773 )

♀

IMPC - UCD

decreased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - UCD

immune system

increased eosinophil cell number ( J:211773 )

IMPC - UCD

decreased lymphocyte cell number ( J:211773 )

IMPC - UCD

decreased monocyte cell number ( J:211773 )

♂

IMPC - UCD

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - UCD

reproductive system

female infertility ( J:211773 )

♀

IMPC - UCD

male infertility ( J:211773 )

♂

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

♂

IMPC - UCD

microphthalmia ( J:211773 )

♂

IMPC - UCD