Phenotypes for Cfap70 MGI:7587862 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cfap70^em2Chnsr/Cfap70^em2Chnsr
Genetic Background	involves: C57BL/6J

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Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cfap70^em2Chnsr mutation (0 available); any Cfap70 mutation (39 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal sperm flagellum morphology ( J:338031 )

abnormal sperm axoneme morphology ( J:338031 )

• partial loss of peripheral doublet microtubules in sperm flagella

absent sperm axonemal central pair ( J:338031 )

absent sperm flagellum ( J:338031 )

• sperm exhibit short, coiled, and absent flagella

coiled sperm flagellum ( J:338031 )

short sperm flagellum ( J:338031 )

oligozoospermia ( J:338031 )

asthenozoospermia ( J:338031 )

male infertility ( J:338031 )

cellular

abnormal sperm flagellum morphology ( J:338031 )

abnormal sperm axoneme morphology ( J:338031 )

• partial loss of peripheral doublet microtubules in sperm flagella

absent sperm axonemal central pair ( J:338031 )

absent sperm flagellum ( J:338031 )

• sperm exhibit short, coiled, and absent flagella

coiled sperm flagellum ( J:338031 )

short sperm flagellum ( J:338031 )

oligozoospermia ( J:338031 )

asthenozoospermia ( J:338031 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
oligoasthenoteratozoospermia		DOID:0070311		J:338031

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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