Phenotypes Associated with This Genotype

Genotype
MGI:7593968

• Allelic Composition: Adgrv1^m1/Adgrv1^m1
• Genetic Background: CBACa.KM-Adgrv1^m1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hearing/vestibular/ear

hearing/vestibular/ear phenotype ( J:273686 )

N • normal cochlear inner hair cell morphology

decreased outer hair cell stereocilia number ( J:273686 )

• severely reduced at age P56

organ of Corti degeneration ( J:273686 )

• at age P56

increased or absent threshold for auditory brainstem response ( J:273686 )

• at age P14, P21 and P56

deafness ( J:273686 )

• at age P14, P21 and P56

nervous system

decreased outer hair cell stereocilia number ( J:273686 )

• severely reduced at age P56

cochlear ganglion hypoplasia ( J:273686 )

• severely degenerated in the basal turn of cochlea at age P56

vision/eye

vision/eye phenotype ( J:273686 )

N • normal vision at age P56

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Usher syndrome type 2C		DOID:0110839	OMIM:605472	J:273686