Phenotypes Associated with This Genotype

Genotype
MGI:7643971

• Allelic Composition: Dock8^tm1Ysfk/Dock8^tm1Ysfk; Tg(TcrAND)53Hed/0
• Genetic Background: involves: C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

dermatitis ( J:305132 )

• mice develop an atopic dermatitis-like skin disease, with increased skin inflammation and scratching behavior

integument

dermatitis ( J:305132 )

• mice develop an atopic dermatitis-like skin disease, with increased skin inflammation and scratching behavior

increased pruritus ( J:305132 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
atopic dermatitis		DOID:3310	OMIM:603165 OMIM:PS603165	J:305132