Phenotypes for Col17a1 Lamc2 MGI:7709432 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Col17a1^em8Dcr/Col17a1⁺ Lamc2^jeb/Lamc2^jeb
Genetic Background	B6.Cg-Lamc2^jeb Col17a1^em8Dcr/Dcr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col17a1^em8Dcr mutation (1 available); any Col17a1 mutation (51 available)
Lamc2^jeb mutation (4 available); any Lamc2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

dermal-epidermal separation ( J:352187 )

decreased skin tensile strength ( J:352187 )

• disease onset is faster and more severe in the presence of one null allele of Col17a1

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
junctional epidermolysis bullosa		DOID:3209		J:352187

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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