Analysis Tools
behavior/neurological
|
• mice stop struggling earlier in the tail suspension test, indicating depression-like behavior
|
|
• mice display decreased locomotor activity and spend much less time in the center of the open-field test
• mice are afraid to enter into the open arms in the elevated plus maze test
• in the dark-light transition test, mice exhibit fewer transitions from the dark zone to the light zone and spend less time in the light zone
• treatment of mice with VLA-4 or CD6 neutralizing antibodies has no effect on anxiety symptom
|
|
• mice spend much less time in the center of the open-field test
|
|
• in the social novelty task, mice spend reduced contact time with a stranger mouse, indicating less motivation and curiosity
|
hematopoietic system
|
• naive CD4+ T cells exhibit highly fragmented mitochondria
• many small, diverse mitochondria dispersed in the cytoplasm of naive CD4+ T cells
|
immune system
|
• naive CD4+ T cells exhibit highly fragmented mitochondria
• many small, diverse mitochondria dispersed in the cytoplasm of naive CD4+ T cells
|
