Phenotypes Associated with This Genotype

Genotype
MGI:7748790

• Allelic Composition: Opr1/Opr1⁺
• Genetic Background: B6.Cg-Opr1/Boc

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Opr1/Opr1⁺ mice exhibit an optic ring in the fundus and optic cupping at 4 weeks of age.

vision/eye

abnormal posterior eye segment morphology ( J:355415 )

abnormal optic nerve morphology ( J:355415 )

• optic ring and optic cupping are generally found by 4 weeks of age, and sometimes earlier

optic nerve cupping ( J:355415 )

nervous system

abnormal optic nerve morphology ( J:355415 )

• optic ring and optic cupping are generally found by 4 weeks of age, and sometimes earlier

optic nerve cupping ( J:355415 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
coloboma		DOID:12270	OMIM:120200 OMIM:120300 OMIM:216820	J:355415