Phenotypes Associated with This Genotype

Genotype
MGI:7779652

• Allelic Composition: opr2/opr2
• Genetic Background: B6.CALB-opr2/BocJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal optic nerve morphology ( J:358068 )

• Background Sensitivity: optic ring and optic cupping found at 4 weeks of age, with the penetrance greater on CALB/RkJ than the C57BL/6J congenic

optic nerve cupping ( J:358068 )

vision/eye

abnormal posterior eye segment morphology ( J:358068 )

abnormal optic nerve morphology ( J:358068 )

• Background Sensitivity: optic ring and optic cupping found at 4 weeks of age, with the penetrance greater on CALB/RkJ than the C57BL/6J congenic

optic nerve cupping ( J:358068 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
coloboma		DOID:12270	OMIM:120200 OMIM:120300 OMIM:216820	J:358068