Phenotypes Associated with This Genotype

Genotype
MGI:7780165

• Allelic Composition: Opr3/Opr3⁺
• Genetic Background: B6.Cg-Opr3/BocJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal posterior eye segment morphology ( J:358340 )

abnormal optic nerve morphology ( J:358340 )

• optic ring is found by 3 to 4 weeks of age in heterozygotes and homozygotes but with incomplete penetrance such that only 30% of offspring from heterozygotes bred to wild type show the phenotype and only 50% to 70% of offspring from homozygotes bred to wild type show the phenotype

optic nerve cupping ( J:358340 )

nervous system

abnormal optic nerve morphology ( J:358340 )

• optic ring is found by 3 to 4 weeks of age in heterozygotes and homozygotes but with incomplete penetrance such that only 30% of offspring from heterozygotes bred to wild type show the phenotype and only 50% to 70% of offspring from homozygotes bred to wild type show the phenotype

optic nerve cupping ( J:358340 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
coloboma		DOID:12270	OMIM:120200 OMIM:120300 OMIM:216820	J:358340