growth/size/body
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• male mice fed a standard diet gain significantly more weight than heterozygous littermates between 5 and 11 weeks of age
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homeostasis/metabolism
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• at 10-11 weeks of age, male mice show significantly higher plasma levels of 3-deoxyglucosone, methylglyoxal, and dimethylglyoxal than heterozygous littermates
• however, plasma glyoxal levels are normal
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• male mice are hyperglycemic at 10-11 weeks of age
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