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Phenotypes Associated with This Genotype
Genotype
MGI:7868187
ht3
Allelic
Composition		 Tmem151bnmf389/Tmem151b+
Genetic
Background		 B6N.B6J-Tmem151bnmf389/FrkJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tmem151bnmf389 mutation (0 available); any Tmem151b mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal seizure response to electrical stimulation ( J:362012 )
• From assessments at 6 to 8 weeks of age, heterozygous females have a mean seizure threshold of 35.49 + 2.85 iRMS compared with 43.16 + 2.21 iRMS for C57BL/6NJ wildtype controls; heterozygous males have a mean seizure threshold of 41.94 + 1.45 iRMS compared with 47.38 iRMS for C57BL/6NJ wildtype controls.

nervous system
abnormal seizure response to electrical stimulation ( J:362012 )
• From assessments at 6 to 8 weeks of age, heterozygous females have a mean seizure threshold of 35.49 + 2.85 iRMS compared with 43.16 + 2.21 iRMS for C57BL/6NJ wildtype controls; heterozygous males have a mean seizure threshold of 41.94 + 1.45 iRMS compared with 47.38 iRMS for C57BL/6NJ wildtype controls.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory