anti-cleaved Notch1 (Val1744) antibody (anti-NICD) (#2421) MGI Antibody Detail

Antibody
Detail

Antibody

Name:	anti-cleaved Notch1 (Val1744) antibody (anti-NICD) (#2421)
Synonym:	anti-NICD
Host:	rabbit
Type:	Polyclonal
Note:	Antibody from Cell Signaling Technology (#2421). Antibody detects cytosolic domain of Notch1 only when cleaved between Gly1743 and Val1744; does not recognize full-length Notch1 or Notch1 cleaved at other positions. This antibody is discontinued (2016).
MGI Accession ID:	MGI:2676300

Antigen

Name:	Notch 1 (Val1744) peptide
Species:	human
Region covered:	residues surrounding amino acid 1744
Note:	KLH-coupled synthetic peptide

Gene

Notch1 notch 1

Expression

Gene Expression Data (242 results)

References

J:85474 Cheng HT, et al., Development. 2003 Oct;130(20):5031-5042
J:102528 Barsi JC, et al., Mech Dev. 2005 Oct;122(10):1106-17
J:124179 Del Monte G, et al., Dev Dyn. 2007 Sep;236(9):2594-614
J:234164 Geffers I, et al., J Cell Biol. 2007 Jul 30;178(3):465-76
J:161418 Takahashi J, et al., Dev Biol. 2010 Jun 15;342(2):134-45
J:172573 Niwa Y, et al., Genes Dev. 2011 Jun 1;25(11):1115-20
J:172692 Mysliwiec MR, et al., J Biol Chem. 2011 May 13;286(19):17193-204
J:175387 Wu X, et al., Dev Biol. 2011 Aug 15;356(2):337-49
J:197325 Lin X, et al., Proc Natl Acad Sci U S A. 2013 May 14;110(20):8236-41
J:204466 Tadeu AM, et al., Development. 2013 Sep;140(18):3777-86
J:229936 Cano E, et al., Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):656-61
J:236406 Takada Y, et al., Development. 2016 Oct 1;143(19):3532-3539
J:243375 Choi D, et al., J Clin Invest. 2017 Apr 03;127(4):1225-1240

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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