About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:30828 Ang SL, et al., A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain. Development. 1996 Jan;122(1):243-52
Assay type: RNA in situ
MGI Accession ID: MGI:1275928
Gene symbol: Egr2
Gene name: early growth response 2
Probe: Krox-20 probe2
Probe preparation: RNA
Results
Specimen 5B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: rhombomere 3 Present 5B
TS13: rhombomere 5 Present 5B

Specimen 5E: embryonic day 8.5; Otx2tm1Sla/Otx2tm1Sla (more )
Structure Level Pattern Image Note
TS13: rhombomere 3 Present 5E In mutants, the first band of expression in the neural rube occurred close to or at the anterior-most end of the embryo. These results demonstrate that in homozygous mutants, neural tissues anterior to rhombomere 3 have been deleted.
TS13: rhombomere 5 Present 5E In mutants, the first band of expression in the neural rube occurred close to or at the anterior-most end of the embryo. These results demonstrate that in homozygous mutants, neural tissues anterior to rhombomere 3 have been deleted.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/22/2024
MGI 6.24
The Jackson Laboratory