Gene Expression Data
Assay Details
Assay
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Reference:
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J:30828
Ang SL, et al., A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain. Development. 1996 Jan;122(1):243-52
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1275928
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Gene symbol:
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Egr2
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Gene name:
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early growth response 2
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Results
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Specimen
5B:
embryonic day 8.5
(more )
Specimen
5B:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
5E:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
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Otx2tm1Sla/Otx2tm1Sla
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS13: rhombomere 3 |
Present |
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5E
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In mutants, the first band of expression in the neural rube occurred close to or at the anterior-most end of the embryo. These results demonstrate that in homozygous mutants, neural tissues anterior to rhombomere 3 have been deleted.
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TS13: rhombomere 5 |
Present |
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5E
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In mutants, the first band of expression in the neural rube occurred close to or at the anterior-most end of the embryo. These results demonstrate that in homozygous mutants, neural tissues anterior to rhombomere 3 have been deleted.
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