Otx2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:49817 Acampora D, et al., Visceral endoderm-restricted translation of otx1 mediates recovery of otx2 requirements for specification of anterior neural plate and normal gastrulation. Development. 1998 Dec;125(24):5091-104
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:1309367
Gene symbol:	Otx2
Gene name:	orthodenticle homeobox 2

Antibody:	anti-OTX2
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase

Results

3A ©

Specimen 3A: embryonic day 7.5; Otx2^tm1Pas/Otx2^tm1Pas (more

)
Note: Specificity of alphaOTX2 shown in Otx2-/- embryos.

Structure	Level	Pattern	Image	Note
TS11: embryo	Absent		3A

3C ©

Specimen 3C: embryonic day 6.5 (more

)

Structure	Level	Pattern	Image	Note
TS9: embryo ectoderm	Present		3C
TS9: extraembryonic visceral endoderm	Present		3C

3E ©

3F ©

Specimen 3E/F: embryonic day 7.75 (more

)

Structure	Level	Pattern	Image	Note
TS11: mesendoderm	Present		3E , 3F	Otx2 is present in the neuroectoderm and axial mesendoderm at 7.75 d.p.c.
TS11: neural ectoderm	Present		3E , 3F	Otx2 is present in the neuroectoderm and axial mesendoderm at 7.75 d.p.c.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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