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Gene Expression Data
Assay Details
Assay
Reference: J:49322 Zuniga A, et al., Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity. Development. 1999 Jan;126(1):13-21
Assay type: RNA in situ
MGI Accession ID: MGI:1314735
Gene symbol: Hoxd13
Gene name: homeobox D13
Probe: Hoxd13 probe4
Probe preparation: labelled with digoxigenin RNA
Assay notes: All results were confirmed by also analyzing ld<In2>/Xt<H> intercrosses.
Results
Specimen 3e: embryonic day 9.75 (more )
Note: 28 somites.
Structure Level Pattern Image Note
TS15: forelimb bud Present Regionally restricted 3e The expression domain is smaller than the Hoxd11 domain in the contralateral limb bud (revealing posterior nesting).
Specimen 3f: embryonic day 9.75; Fmn1ld-Is(17;In2)1Gso/Fmn1ld-Is(17;In2)1Gso (more )
Note: 28 somites.
Structure Level Pattern Image Note
TS15: forelimb bud Present Regionally restricted 3f The expression domain is smaller than the Hoxd11 domain in the contralateral limb bud (revealing posterior nesting).
Specimen 3g: embryonic day 9.75; Gli3Xt-J/Gli3Xt-J (more )
Note: 28 somites.
Structure Level Pattern Image Note
TS15: forelimb bud Present Uniform 3g Posterior restriction of expression is lost.
Specimen 3h: embryonic day 9.75; Gli3Xt-J/Gli3Xt-J, Fmn1ld-Is(17;In2)1Gso/Fmn1ld-Is(17;In2)1Gso (more )
Note: 28 somites.
Structure Level Pattern Image Note
TS15: forelimb bud Present Uniform 3h Posterior restriction of expression is lost.
Specimen not shown: embryonic day 10.75; Gli3Xt-J/Gli3Xt-J, Fmn1ld-Is(17;In2)1Gso/Fmn1ld-Is(17;In2)1Gso (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted Aberrant expression persists in the proximal limb-bud mesenchyme of Xt;ld double mutant embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory