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Gene Expression Data
Assay Details
Assay
Reference: J:44517 Peters H, et al., Pax1 and Pax9 synergistically regulate vertebral column development. Development. 1999 Dec;126(23):5399-408
Assay type: RNA in situ
MGI Accession ID: MGI:1349752
Gene symbol: Col2a1
Gene name: collagen, type II, alpha 1
Probe: pMCol2a1-1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5. D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS16: tail somite Present Regionally restricted 5D A segmented expression pattern is detected in the somites and a ventral domain is also detected in the somites between the the fore and hindlimbs.
TS16: trunk sclerotome Present Regionally restricted 5D A segmented expression pattern is detected in the somites and a ventral domain is also detected in the somites between the the fore and hindlimbs.
TS16: trunk somite Present Regionally restricted 5D A segmented expression pattern is detected in the somites and a ventral domain is also detected in the somites between the the fore and hindlimbs.
Specimen 5. E: embryonic day 10.5; Pax1tm1Neu/Pax1tm1Neu (more )
Structure Level Pattern Image Note
TS17: tail somite Present Regionally restricted 5E A segmented expression pattern is detected in the somites and a ventral domain is also detected in the somites between the the fore and hindlimbs.
TS17: trunk sclerotome Present Regionally restricted 5E A segmented expression pattern is detected in the somites and a ventral domain is also detected in the somites between the the fore and hindlimbs.
TS17: trunk somite Present Regionally restricted 5E A segmented expression pattern is detected in the somites and a ventral domain is also detected in the somites between the the fore and hindlimbs.
Specimen 5. F: embryonic day 10.5; Pax1tm1Neu/Pax1tm1Neu, Pax9tm1Rbal/Pax9tm1Rbal (more )
Structure Level Pattern Image Note
TS17: tail somite Present Regionally restricted 5F A segmented expression pattern is detected in the somites. A ventral domain is also detected in the somites between the the fore and hindlimbs but is expressed at a much lower level.
TS17: trunk sclerotome Present Regionally restricted 5F A segmented expression pattern is detected in the somites. A ventral domain is also detected in the somites between the the fore and hindlimbs but is expressed at a much lower level.
TS17: trunk somite Present Regionally restricted 5F A segmented expression pattern is detected in the somites. A ventral domain is also detected in the somites between the the fore and hindlimbs but is expressed at a much lower level.
Specimen 5. G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trunk somite Present Regionally restricted 5G A segmented expression pattern is detected in the somites. A ventral domain is also detected in the somites between the the fore and hindlimbs but is expressed at a much lower level.
Specimen 5. H: embryonic day 10.5; Pax1tm1Neu/Pax1tm1Neu, Pax9tm1Rbal/Pax9tm1Rbal (more )
Structure Level Pattern Image Note
TS17: trunk somite Present Regionally restricted 5H A segmented expression pattern is detected in the somites. A ventral domain is also detected in the somites between the the fore and hindlimbs but is expressed at a much lower level.
Specimen 5. I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trunk sclerotome Present 5I
Specimen 5. J: embryonic day 10.5; Pax1tm1Neu/Pax1tm1Neu, Pax9tm1Rbal/Pax9tm1Rbal (more )
Structure Level Pattern Image Note
TS17: trunk sclerotome Present 5J Expression in the double mutant is less then in wild type due to the size reduction of the ventromedial region of the sclerotome in the double mutant, not due an inability of the sclerotome to express Col2a1.
Specimen 6. E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: axial skeleton Strong Regionally restricted 6E Expression is strong in the chondrifying anlagen of the vertebral bodies and weak in the intervertebral dics.
TS20: notochord Present 6E
Specimen 6. F: embryonic day 12.5; Pax1tm1Neu/Pax1tm1Neu (more )
Structure Level Pattern Image Note
TS20: axial skeleton Present Regionally restricted 6F Expression is detected in the vertebral bodies which are are smaller in Pax1 mutants.
TS20: notochord Present 6F
Specimen 6. G: embryonic day 12.5; Pax1tm1Neu/Pax1tm1Neu, Pax9tm1Rbal/Pax9tm1Rbal (more )
Structure Level Pattern Image Note
TS20: notochord Present 6G
TS20: axial skeleton Present Regionally restricted 6G Expression is detected in irregular remnants of the vertebral bodies and is almost absent in the region dorsal to the notochord.
Specimen 6. H: embryonic day 12.5; Pax1tm1Neu/Pax1tm1Neu, Pax9tm1Rbal/Pax9tm1Rbal (more )
Structure Level Pattern Image Note
TS20: notochord Present 6H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/09/2024
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