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Gene Expression Data
Assay Details
Assay
Reference: J:53473 Niederreither K, et al., Retinoic acid synthesis and hindbrain patterning in the mouse embryo. Development. 2000 Jan;127(1):75-85
Assay type: RNA in situ
MGI Accession ID: MGI:1350661
Gene symbol: Meis2
Gene name: Meis homeobox 2
Probe: Meis2 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4B WT: embryonic day 8.75 (more )
Structure Level Pattern Image Note
TS14: future midbrain Present 4B WT
TS14: rhombomere 2 Present 4B WT
TS14: rhombomere 3 Present 4B WT
Specimen 4B -/-: embryonic day 8.75; Aldh1a2tm1Ipc/Aldh1a2tm1Ipc (more )
Structure Level Pattern Image Note
TS14: future midbrain Present 4B -/- Expression in this mutant is similar to that of wild-type embryos.
TS14: future hindbrain Present Regionally restricted 4B -/- Expression has a well-defined rostral border, but extends abnormally throughout the cudal hindbrain (bracket).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory