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Gene Expression Data
Assay Details
Assay
Reference: J:62163 Handler M, et al., Presenilin-1 regulates neuronal differentiation during neurogenesis. Development. 2000 Jun;127(12):2593-606
Assay type: RNA in situ
MGI Accession ID: MGI:1859934
Gene symbol: Notch1
Gene name: notch 1
Probe: Notch1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7Aa: embryonic day 11.5; Psen1tm1Shn/Psen1+ (more )
Structure Level Pattern Image Note
TS19: diencephalon Moderate 7Aa
TS19: telencephalon Moderate 7Aa
Specimen 7Ac: embryonic day 11.5; Psen1tm1Shn/Psen1+ (more )
Structure Level Pattern Image Note
TS19: forebrain Moderate Regionally restricted 7Ac Expression is in the ganglionic eminence.
Specimen 7Ae: embryonic day 11.5; Psen1tm1Shn/Psen1+ (more )
Structure Level Pattern Image Note
TS19: diencephalon Moderate 7Ae
TS19: telencephalon Moderate 7Ae
Specimen 7Ab: embryonic day 11.5; Psen1tm1Shn/Psen1tm1Shn (more )
Structure Level Pattern Image Note
TS19: diencephalon Moderate 7Ab Expression in this mutant is similar to wild-type.
TS19: telencephalon Moderate 7Ab Expression in this mutant is similar to wild-type.
Specimen 7Ad: embryonic day 11.5; Psen1tm1Shn/Psen1tm1Shn (more )
Structure Level Pattern Image Note
TS19: forebrain Moderate Regionally restricted 7Ad Expression is in the ganglionic eminence. Expression in this mutant is similar to wild-type.
Specimen 7Af: embryonic day 11.5; Psen1tm1Shn/Psen1tm1Shn (more )
Structure Level Pattern Image Note
TS19: diencephalon Moderate 7Af Expression in this mutant is similar to wild-type.
TS19: telencephalon Moderate 7Af Expression in this mutant is similar to wild-type.
Specimen 8Aa: embryonic day 9.5; Psen1tm1Shn/Psen1+ (more )
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Strong 8Aa
TS15: future hindbrain Moderate 8Aa
TS15: future spinal cord Moderate 8Aa
Specimen 8Ab: embryonic day 9.5; Psen1tm1Shn/Psen1tm1Shn (more )
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Strong 8Ab Expression in this mutant is similar to wild-type.
TS15: future hindbrain Moderate 8Ab Expression in this mutant is similar to wild-type.
TS15: future spinal cord Moderate 8Ab Expression in this mutant is similar to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory