Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:73067
Li JY, et al., Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression. Development. 2001 Dec;128(24):4979-91
|
Assay type:
|
RNA in situ
|
MGI Accession ID:
|
MGI:2158711
|
Gene symbol:
|
Otx2
|
Gene name:
|
orthodenticle homeobox 2
|
Probe:
|
pOtd9
|
Probe preparation:
|
Antisense RNA
|
|
Results
|
Specimen
1C left:
embryonic day 7.5
(more )
Note: This embryo was at early head fold.
Specimen
1C left:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 7.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Note:
|
This embryo was at early head fold.
|
Structure |
Level |
Pattern |
Image |
Note |
TS11: neural ectoderm |
Present |
Regionally restricted |
1C left
|
Expression is present in the anterior neuroectoderm.
|
TS11: embryo |
Present |
Regionally restricted |
1C left
|
Expression is present in the anterior third of the embryo.
|
Specimen
1C right:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Gbx2tm1.1Mrt/Gbx2tm1.1Mrt
|
Age:
|
embryonic day 7.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Note:
|
This embryo was at early head fold.
|
Structure |
Level |
Pattern |
Image |
Note |
TS11: embryo |
Present |
Regionally restricted |
1C right
|
The expression is the same in the mutant as in the wild type; expression is present in the anterior third of the embryo.
|
Specimen
1D left:
embryonic day 8.0
(more )
Note: This embryo was at late head fold.
Specimen
1D left:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 8.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Note:
|
This embryo was at late head fold.
|
Specimen
1D right:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Gbx2tm1.1Mrt/Gbx2tm1.1Mrt
|
Age:
|
embryonic day 8.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Note:
|
This embryo was at late head fold.
|
Structure |
Level |
Pattern |
Image |
Note |
TS12: embryo |
Present |
Regionally restricted |
1D right
|
Expression in the mutant is expanded caudally relative to the wild type, particularly in the midline.
|
Specimen
2E left:
embryonic day 7.5
(more )
Specimen
2E left:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 7.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS11: embryo |
Present |
Regionally restricted |
2E left
|
Expression is present in the anterior of the embryo.
|
Specimen
2E right:
embryonic day 7.5
(more )
Specimen
2E right:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 7.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS11: embryo |
Present |
Regionally restricted |
2E right
|
Expression is present in the anterior of the embryo.
|
Specimen
2F:
embryonic day 8.5
(more )
Specimen
2F:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 8.5
|
Age Note:
|
Theiler stage of this specimen assigned by curators from EMAGE.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS12: embryo |
Present |
Regionally restricted |
2F
|
|
Specimen
2J inset:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Gbx2tm1.1Mrt/Gbx2tm1.1Mrt
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: embryo |
Present |
Regionally restricted |
2J inset
|
Expression in the mutant is expanded posteriorly compared to the wild type, to the presumptive rhombomere 3/4 border.
|
|